Expression of interleukin (IL)-11 and IL-11 receptor in human colorectal adenocarcinoma: IL-11 up-regulation of the invasive and proliferative activity of human colorectal carcinoma cells
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چکیده
منابع مشابه
Expression of interleukin (IL)-11 and IL-11 receptor in human colorectal adenocarcinoma: IL-11 up-regulation of the invasive and proliferative activity of human colorectal carcinoma cells.
Previous investigations have shown that interleukin (IL)-11/IL-11 receptor alpha-chain (IL-11Ralpha), a member of the PI3K, MAPK and JAK-STAT activating family of cytokines/receptors, correlates with the regulation of tumor progression. In this study, we established the IL-11/IL-11Ralpha expression profile in human colorectal adenocarcinoma (CRC) and clarified its signaling pathway and role in ...
متن کاملRecombinant soluble interleukin-11 (IL-11) receptor alpha-chain can act as an IL-11 antagonist.
We have expressed a soluble N-glycosylated form of the murine interleukin-11 (IL-11) receptor alpha-chain (sIL-11R) and examined signaling in cells expressing the gp130 molecule. In the presence of gp130 but not the transmembrane IL-11R, the sIL-11R mediated IL-11-dependent differentiation of M1 leukemic cells and proliferation in Ba/F3 cells. Early intracellular events stimulated by the sIL-11...
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[73] Assignee: The United States of America as Vector Processor Architecture for Real-Time Control”, IEEE, Nov. 1989. Ling et al., A VLSI Robotics Vector Processor For Real-Time Control; IEEE, 1988. Amin-Javaheri et al., “Systolic Architecture for the Manipulator Inertia Matrix”, IEEE Dec. 1988. Fijany et al., “A Class of Parallel Algorithms for Computation of the Manipulator Inertia Matrix”, N...
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Lipcznska-Kochany et al. Charge-transfer complexation with a new class of electron acceptors made of a tryptycenequinone unit. Chemistry Letters (1982), (7), pp 1075-8 (abstract).* P. Bartlett et al., Triptycene (9,l&o-Benzenoanthracene), J. Am. Chem. SOC. 64:2649-53, 1942. P. Bedworth et al., The Synthesis of a symmetrically substituted a-octa(isopentoxy)anthralocyanine, J. Chem. SOC. Chem. Co...
متن کاملExpression of interleukin (IL)-11 receptor by the human endometrium in vivo and effects of IL-11, IL-6 and LIF on the production of MMP and cytokines by human endometrial cells in vitro.
Interleukin (IL)-6, leukaemia inhibitory factor (LIF) and IL-11 belong to the same family of cytokines whose receptors utilize gp130 as the signalling molecule. We have investigated the expression of the IL-11 receptor, IL-11Ralpha, protein in the human endometrium in vivo and the effects of IL-6, LIF and IL-11 on the production of metalloproteinases (MMPs) and cytokines by cultured endometrial...
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ژورنال
عنوان ژورنال: International Journal of Oncology
سال: 2006
ISSN: 1019-6439,1791-2423
DOI: 10.3892/ijo.29.4.869